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A collection of questions and answers from a csfa sfa 203 course, covering topics from weeks 5 to 8. It offers insights into various aspects of microbiology, pharmacology, and cancer treatment, including bacterial infections, antibiotic mechanisms, anti-cancer drugs, and immune system modulation. Useful for students seeking to review key concepts and test their understanding.
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-CSFA SFA 203 Week 5 Test -CSFA SFA 203 Week 6 Test -CSFA SFA 203 Week 7 Test -CSFA SFA 203 Week 8 Test
CSFA SFA 203 Week 5 Test Where is Staph aureus most likely to cause an infection: - ANSWER Skin Tuberculosis and leprosy are known and what type of bacterial diseases? -Mycobacteria ANSWER
Viruses are obligate intracellular _________ composed of either DNA or RNA wrapped ina protein nucleocapsule - ANSWER Parasites
Reactive Airway Disease causes decreased oxygenation of the lungs secondary to thetracheobronchial constriction - ANSWER True
Which of the following is considered the gold standard for identification of microbes -ANSWER Cultures
Penicillin is strong enough to cause minor dermatological allergic reaction but not lifethreatening allergic reactions such as anaphylactic shock - ANSWER False
Tuberculosis often presents with pulmonary symptoms but may involve lymph nodes,bones, skin, and __________ - ANSWER Meninges
Bacteriostatic agents kill bacteria and prevent proliferation - ANSWER False Common Gram-negative pathogens that normally inhabit the GI tract fall into whatgroup? - ANSWER Enterics
Currently there are three categories of anti-HIV drugs: nucleoside analogs,non-nucleoside reverse transcriptase inhibitors and ____________ inhibitors - ANSWER Protease When Candida infects the mouth it is called _________ - ANSWER Thrush The sensitivity of bacteria to various antibiotics is determined by growing cultures in thepresence of the antibiotics of interest. This is called: - ANSWER Sensitivity determination First generation cephalosporins are effective against Gram-positive organisms butsubsequent generations reduced it effectiveness to Gram-positive organisms - ANSWER True Third generation cephalosporins are effective against many Gram-negatives and theypenetrate the brain well - ANSWER True
First generation cephalosporins are not effective against most skin and skin structureinfections - ANSWER False
It is more difficult for bacteria to develop resistance to two drugs with differentmechanisms than to develop resistance to a single agent - ANSWER True
Broad spectrum penicillins are more hydrophilic than other drugs but cannot passthrough selective pores - ANSWER False
All alkylating agents are toxic to ______ cells - ANSWER Hemotologic Which antibiotic anticancer agent is extensively used to treat pediatric sarcomas? -ANSWER Dactinomycin
Cancer cells become resistant to anticancer agents through a variety of mechanismsincluding enhanced production that repair damaged _________ - ANSWER DNA
Cross-linking DNA promotes separation of DNA strands - ANSWER False Tumor cells are derived from normal cells in which proliferation is poorly controlled -ANSWER True
Hematopoietic Agents are ________ produced by cultured mammalian cells -Glycoproteins ANSWER
Alkylating agents are generally more effective against fast growing tumors than otherclasses of tumors - ANSWER False
Some tumors become resistant to several classes of antitumor agents, even though theyhave never been exposed to some of these agents. This is called _________ drug resistance - ANSWER Multi-drug Many anticancer drugs cause toxicity that unrelated to cell growth rate -True ANSWER
Antimetabolites are cell-cycle specific agents which prevent synthesis of nucleotides orinhibit enzymes by mimicking nucleotides - ANSWER True
Tumor cells are remarkably similar to noncancerous human cells - ANSWER True
Leukemias and lymphomas are derived from _________ cells - ANSWER Immune One of the notable side effects of cyclophosphamide is hemorrhagic cystitis -True ANSWER
_________ induce a number of gene products in cells that are interferon receptor positive- ANSWER Interferons
Most anticancer hormones act as agonists that inhibit tumor cell growth or asantagonists that compete with endogenous growth promoting hormones - ANSWER True Bifunctional alkylation is more toxic than single strand alkylation because it is less easily________ - ANSWER Repaired
The most commonly used antibiotic anticancer agents are Adriamycin, Actinomycin D,mitomycin C and _________ - ANSWER Bleomycin
Hormonal anticancer drugs ____________ receptors, preventing endogenousgrowth-promoting hormones from binding - ANSWER Antagonize
CSFA SFA 203 Week 7 Test What is the immunostimulating agent that is indicated for Kaposi's sarcoma? -ANSWER Interferons
Immunosuppressants not only help prevent rejection of transplanted organs but alsoprevents erythroblastosis fetalis - ANSWER True
Which antigout agent fosters the elimination of uric acid release from leukemia cells? -
Medication given by injection in the muscle is termed: - ANSWER IM Corticosteroids _________ prebronchial inflammation - ANSWER Decrease The parasympathetic system expends energy - ANSWER False Most anticancer agents act by inhibiting cell __________ - ANSWER Proliferation One site in the body that is protected as far as antibiotic therapy goes (meaning it isharder to get tissue in that area to respond to the drug) is: - ANSWER Joint
The term tolerance means _________ response to a drug - ANSWER Decreased Bronchonstriction results from the effects of acetycholine, histamine and _________mediators released within the bronchial walls - ANSWER Inflammatory
Reactive airway is also known as ____________ - ANSWER Asthma Parkinson's Disease is caused by decreased _________ neurotransmission -Dopamine ANSWER
The peripheral nervous system is divided into the somatic nervous and ___________system - ANSWER Autonomic
Third generation chephalosporins are effective against many Gram-negatives and arenot destroyed by cephalosporinases - ANSWER True
The duration of a drug is _________ -therapeutic ANSWER Length of time for which a drug is
Patients with chronic bronchitis experience chronic _________ as a result of airwayobstruction and inflammation - ANSWER Dyspnea
Most drugs, toxins and metabolites are excreted in the _______ - ANSWER Urine Ibuprofen can cause GI irritation or ulceration when used in high dosage -True ANSWER
The last thing to do when forming a story about a drug is to associate, ask, and -ANSWER Predict
__________ is commonly given pre-op to patients to reduce acid in the GI tract -ANSWER Reglan
Axid is an acid reducing agent - ANSWER True Pitocin is used typically in which surgical specialty? - ANSWER Obsterics As a first assistant, what is the first response if a patient has an allergic reaction to adrug? - ANSWER Maintain sterility of the field
Dependence occurs when a patient needs a drug to function normally - ANSWER True Direct vasodilators ___________ smooth muscle cells - ANSWER Relax Which of the following antihypertensive (diuretics) must be used cautiously to avoiddehydration and requires potassium levels to be followed closely - ANSWER Loop