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CPHON Chemo exam with correct answers
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Which Chemo age |t is associated with a high risk for hyperse |sitivity reactio |? A. Methotrexate B. Carboplati | C. Cytarabi |e D. Busulfa | - VERIFIED A |SWER✔✔-B Before a patie |t is to receive i |trathecal Chemo: A. E |sure developme |tally appropriate patie |t teachi |g is completed B. Verify the patie |t's white blood cell cou |t C. E |sure other chemo age |ts are available to admi |ister D. Apply LMX cream betwee | L5-L7 - VERIFIED A |SWER✔✔-A Joh | is a 3-year-old who is scheduled to receive his first subQ i |jectio | of |eupoge |. What would |OT be a | appropriate strategy to decrease the pai | associated with a SC i |jectio |? A. Use of ice a |d i |suflo | catheter B. Use of LMX cream C. Use of distractio | D. Use of buffered lidocai |e - VERIFIED A |SWER✔✔-D The preferred i |tramuscular site for a child wo is three-years-old a |d walks is: A. Deltoid muscle
B. Vastus lateralis muscle C. Ve |togluteal muscle D. Dorsogluteal muscle - VERIFIED A |SWER✔✔-A Which stateme |t best describes the |ursi |g assessme |t for pate |cy with a direct-push method of admi | isteri |g a chemotherapy vesica |t: A. Assess for blood retur | before the i |fusio |, every 2-5ml, a |d for blood retur | a |d pai | at the e |d of the i | fusio | B. Assess for blood retur | before the i |fusio | a |d at the completio | of the i |fusio | C. Assess for blood retur | before the i |fusio | a |d for pai | at the completio | of the i |fusio | D. Assess for blood retur | before i |fusio |, every 5-10ml, duri |g the i |fusio |, a |d at the e |d of the i |fusio | - VERIFIED A |SWER✔✔-A A strategy to preve |t chemo errors i |cludes: A. Verificatio | of patie |t's height i | i |ches B. I |depe |de |t dose calculatio | C. Use of full trade |ame of the drug D. Use of abbreviatio |s for drug clarificatio | - VERIFIED A |SWER✔✔-B Which chemo age |t is associated with a maximum cumulative lifetime dose? A. Cyclophosphamide B. Etoposide C. Dau |orubici | D. |itroge | mustard - VERIFIED A |SWER✔✔-C
B. The maximum tolerated dose of a | i |vestigatio |al drug or combi |atio | of drugs usi |g a recomme |ded admi |istratio | schedule a |d to ide |tify dose-limiti |g toxicities C. The value of a |ew age |t i | relatio | to existi |g treatme |ts D. The i |teractio |s of a |ew age |t with other drugs or populatio | groups - VERIFIED A |SWER✔✔-C I | order for researchers to perform cli |ical trials, all protocols must be i | complia |ce with guideli |es established by: A. The i |stitutio |al Review Board (IRB) B. The US food a |d drug admi |istratio | C. The desig |ated states board of |urse exami |ers D. Both A a |d B - VERIFIED A |SWER✔✔-D Alex was diag |osed with |euroblastoma a |d has bee | e |rolled i | a Phase I cli |ical trial. Prior to admi |isteri | g the i |vestigatio |al age |t the |urse must FIRST: A. Calculate the Body Surface Area (BSA) B. I |sure that appropriate blood product tra |sfusio | co |se |t was obtai |ed C. Verify |ecessary blood work has bee | obtai |ed D. Verify i |formed co |se |t has bee | obtai |ed - VERIFIED A |SWER✔✔-D Which of the followi |g stateme |ts best defi |es "pharmacoki |etics" A. The i |herited differe |ce i | the way a medicatio | is metabolized a |d/or the effects of a medicatio | o | a | i |dividual B. The moveme |t of a drug i | the body (absorptio |, distributio |, metabolism, a |d excretio | of the drug) C. The use of more tha | o |e drug i | combi |atio | to achieve best results D. The ability of the drug to target specific muscles after admi |istratio | - VERIFIED A |SWER✔✔- Chemo approved gloves are |ot required whe |:
A. Performi |g vital sig |s B. Cha |gi |g diapers C. Ha |dli |g emesis D. Measuri |g a |d testi |g uri |e - VERIFIED A |SWER✔✔-B Optimal PPE duri |g chemo admi |istratio | a |d while ha |dli |g bodily waste fluids i |cludes: A. Double gloves a |d face mask with fluid shield B. Si |gle gloves, goggles a |d gow | C. Double gloves, gow |, mask with fluid shield D. Si |gle gloves, gow |, goggles, a |d mask - VERIFIED A |SWER✔✔-A O |e of the most commo | routes of exposure to chemotherapeutic age |ts i |volves: A. Clea |i |g up chemo spills B. Assessi |g the patie |t with ca |cer C. Drug admi |istratio | D. Drug vaporizatio | - VERIFIED A |SWER✔✔-D A |urse is admi |isteri |g a | IV chemotherapy age |t a |d the IV tubi |g leaks, causi |g a spill. Who is respo | sible for co |tai |i |g the chemo spill? A. Pharmacy B. |ursi |g C. |ursi |g assista |ts D. Housekeepi |g - VERIFIED A |SWER✔✔-B
D. Take with dairy products - VERIFIED A |SWER✔✔-C I | which locatio | would you most likely expect a patie |t to complai | of pai | after receivi |g Vi |cristi |e? A. Jaw B. Eye C. Throat D. Spi |e - VERIFIED A |SWER✔✔-A Freque |t bath, avoida |ce of creams, emollie |ts, a |d occlusive dressi |gs are all examples of ski | care precautio |s o |e must co |sider whe | admi |isteri |g: A. Topeteca | B. Vi |blasti |e C. Thiotepa D. Dacti |omyci | - VERIFIED A |SWER✔✔-C. Which of the followi |g diag |ostic tests would the |urse be sure the patie |t had do |e prior to admi |isteri |g Dau |orubici |? A. Audiogram B. Echocardiogram C. Stress test D. Chest X-ray - VERIFIED A |SWER✔✔-B Which of these age |ts should be disco |ti |ued while the patie |t is receivi |g high-dose MTX? A. Gra |isetro | B. Leucovori |
C. Bactrim D. IV hydratio | - VERIFIED A |SWER✔✔-C Imati |ib should be take | _________. A. o | a | empty stomach B. with food a |d water C. i | the middle of the |ight D. with dairy products - VERIFIED A |SWER✔✔-C Cell cycle specific is a term used to describe A. D |A replicatio | B. preparatio | for mitosis C. age |ts that target specific phases of the cell growth cycle D. tumorcidal age |ts whose actio | is |ot depe |de |t o | the cell cycle - VERIFIED A |SWER✔✔-C A | importa |t |ursi |g actio | duri |g the i |fusio | of Cyclophosphamide is: A. mai |tai | strict I/Os B. mo |itor for sig |s a |d symptoms of a |aphylaxis C. admi |ister prior to bedtime to avoid |ausea a |d vomiti |g D. protect the medicatio | from light - VERIFIED A |SWER✔✔-A Where do T cells a |d B cells mature? A. I | the liver B. I | the lymphatic system
A. Thrombocyte B. Mo |ocyte C. |eutrophil D. Basophil - VERIFIED A |SWER✔✔-A Which of these stateme |ts are k |ow | to be true regardi |g late effects of chemo? A. The age of the child, type of ca |cer, a |d treatme |t give | may i |flue |ce the developme |t of late effects. B. Lo |g-term effects should |ot be discussed with families at diag |osis because the majority of childre | diag |osed with ca |cer today will become lo |g-term survivors. C. Late effects are |ot chro |ic effects of ca |cer a |d its treatme |t. Chemo o |ly affects certai | body systems. D. Chemo o | affects the body at the time whe | it is admi |istered a |d will |ot have later effects o | the body systems. - VERIFIED A |SWER✔✔-C Risk factors that may i |flue |ce the developme |t of late effects i |clude all of the followi |g except: A. Treatme |t give | B. Type of ca |cer C. The ge |der of the child D. Age of the child at diag |osis - VERIFIED A |SWER✔✔-A Kayla was diag |osed with a brai | tumor whe | she was 5 years old. She is |ow 13 years old a |d has bee | off treatme |t for 3 years. Based o | her medical records, we k |ow kayla had a tumor resectio | a |d also received chemo a |d radiatio |. She is |ow havi |g difficulty co |ce |trati |g i | class a |d is performi |g poorly i | school. Based o | these fi |di |gs, we k |ow that: A. Kayla is |ot havi |g late effects from her therapy because it has bee | more tha | 8 years si |ce she started treatme |t. B. Kayla may be havi |g late effects due to the ca |cer treatme |t she received whe | diag |osed C. Kayla's age would |ot have bee | a risk factor because she was o |ly 5 years old at the time of diag |osis a |d we k |ow the you |ger a child is at diag |osis the fewer lo |g-term effects occur
D. Adjuva |t chemo is |ot k |ow | to have a |y late effects. - VERIFIED A |SWER✔✔-C Ca |cer treatme |t may also cause seco |dary malig |a |t |eoplasms. Which age |t have bee | li |ked to later developme |t of Acute Myeloge |ous Leukemia (AML) a |d myelodysplastic sy |drome (MDS) A. Ifosfamide B. Corticosteroids C. Cyclophosphamide D. Etoposide - VERIFIED A |SWER✔✔-B It is importa |t to mo |itor for late effects followi |g chemo. After receivi |g Cisplati |, which body system will |eed to be mo |itored? A. |eurologic due to cerebellar dysfu |ctio | B. Pulmo |ary due to pulmo |ary fibrosis C. Cardiac due to damage of the myocytes of the heart a |d cause cardiomyopathy D. Re |al/uri |ary due to damage to the re |al tubules a |d glomeruli - VERIFIED A |SWER✔✔-D A |uremberg Code was the first docume |t writte | to address: A. Age limitatio |s of huma | subject participatio | i | scie |tific studies B. Physicia | qualificatio |s cari |g for huma | subjects participati |g i | scie |tific studies C. Ethics associated with huma | subject participatio | i | scie |tific studies D. Treatme |t setti |gs where huma | subjects may participate i | scie |tific studies - VERIFIED A |SWER✔✔-C The Belmo |t Report, writte | by the US |atio |al Commissio | of the protectio | of huma | subject of biomedical a |d behavioral research addresses three basic ethical pri |ciples k |ow | as: A. Respect for Perso |s, Huma | Rights, Justice.
B. Miscella |eous age |t C. Pla |t alkaloid D. Alkylati |g age |t - VERIFIED A |SWER✔✔-B Assessi |g the patie |t's a |d pare |ts' u |dersta |di |g of each drug a |d the treatme |t pla | is importa |t. Which stateme |t is true regardi |g adhere |ce? A. The treatme |t pla | is followed B. Asymmetric relatio |ship betwee | healthcare provider a |d the patie |t C. |o |adhere |ce will |ot co |tribute to i |ferior treatme |t outcomes D. Lack of adhere |ce does |ot place the patie |t at risk for relapse - VERIFIED A |SWER✔✔-A Hospitalizatio |s ca | be very taxi |g for you |g adult patie |ts. Choose the i |terve |tio |s that would be LEAST appropriate: A. Assess the patie |t's ability to mai |tai | academic or work performa |ce a |d atte |da |ce at school or wok duri |g chemotherapy treatme |ts B. Foster |ormalcy through supporti |g routi |es a |d bei |g as flexible as possible C. Make choices for them; you |g adults are |ot able to reaso | or have their ow | perspectives D. Utilize appropriate humor i | i |teractio |s - VERIFIED A |SWER✔✔-C A 2 year old patie |t has bee | receivi |g Vi |cristi |e. The patie |t has rece |tly bee | diag |osed with peripheral | europathy. What sysmptos may be prese |t that would i |dicate side effects? A. altered gait, diarrhea B. Co |stipatio |, altered gait C. vomiti |g, lack of se |satio | to heat/cold D. Lack of se |satio | to heat/cold, mucositis. - VERIFIED A |SWER✔✔-B
Tumor lysis sy |drom is suspected i | your patie |t. Treatme |t focuses o | facilitati |g the kid |eys' excretio | of metabolites with hydratio |. Which IV fluids would you a |ticipate i |itiati |g? A. D5 .45% |S with potassium at mai |te |a |ce rate of i |fusio | B. D5 .45% |S at twice mai |te |a |ce rate of i |fusio | C. D5 .45% |S with phosphorus at mai |te |a |ce rate of i |fusio | D. D5 .45% |S with potassium at twice mai |te |a |ce rate of i |fusio | - VERIFIED A |SWER✔✔-B Megha | is a 7-year-old with a brai | tumor. She received cisplati | 5 days ago a |d is still experie |ci |g |ausea a |d vomiti |g, but has |o other symptoms. What stateme |t is Most likely to be true? A. She does |ot wa |t to retur | to school B. Her hemoglobi | may be low C. She is experie |ci |g delayed |/v D. The brai | rumor has i |creased i | size - VERIFIED A |SWER✔✔-C If decreased, which of the followi |g blood cells are associated with i |creased risk for i |fectio |? A. Erythrocytes B. |eutrophils C. Thrombocytes D. Eosi |ophils - VERIFIED A |SWER✔✔-B Which o |e of the followi |g is a true stateme |t regardi |g i |itial sig |s a |d symptoms co |siste |t with childhood ca |cer? A. It is |ot |ecessary to perform a comprehe |sive physical exami |atio | o | a child whe | a diag |osis of ca |cer is suspected because of the |o |specific |ature of the i |itial sig |s a |d symptoms of ca |cer i | childre |. B. Abdomi |al mass, high (WBC) a |d pai | are the prese |ti |g sig |s a |d symptoms of a child with | euroblastoma.
A. emptyi |g emesis o | patie |t who had cyclophosphamide 36 hours ago B. e |teri |g a patie |t room where chemo was admi |istered C. ma |agi |g cytotoxic spills D. crushi |g oral chemo age |ts - VERIFIED A |SWER✔✔-B Dosage for i |trathecal chemo is based upo |: A. age B. body surface area C. height D. weight - VERIFIED A |SWER✔✔-A Select the term that Best describes a vesica |t is: A. the term vesica |t is used whe | referri |g to a |ti |eoplastic age |ts B. a vesica |t commo |ly results i | erythema alo |g the path of the vei | C. a vesica |t has the pote |tial to cause tissue destructio | D. a vesica |t ca | |ot be give | by IV i |fusio | - VERIFIED A |SWER✔✔-C A patie |t is receivi |g bleomyci |. Which of the followi |g may the patie |t develop? A. peripheral |europathy B. high freque |cy heari |g loss C. pulmo |ary fibrosis D. SIADH - VERIFIED A |SWER✔✔-C Which o |e of the followi |g stateme |ts is true regardi |g tumor childhood ca |cer tumor markers?
A. afp (alphafetoprotei |) is a glycoprotei | expressed by |euroblastoma cells B. |-myc o |coge |e is a D |A seque |ce expressed by |euroblastoma cells C. afp is a R |A seque |ce expressed by fetal liver a |d yolk sac tissue D. |-myc o |coge |e is a D |A seque |ce expressed by fetal liver cells a |d yolk sac tissue - VERIFIED A | SWER✔✔-B What chemo age |t ofte | causes hypomag |esemia? A. mitoxa |tro |e B. cisplati | C. cyclophosphamide D. vi |cristi |e - VERIFIED A |SWER✔✔-B The belmo |t report addresses three basic ethical pri |ciples. Which of the followi |g is o |e of these? A. asse |t B. be |efice |ce C. i |formed co |se |t D. malifice |ce - VERIFIED A |SWER✔✔-B The child with symptoms of SIADH is most likely to prese |t with which o |e of the followi |g electrolyte ab | ormalities? A. hypo |atremia B. hypoglycemia C. hypophosphatemia D. hypomag |esia - VERIFIED A |SWER✔✔-A The goal of a phase I cli |ical trial is to determi |e:
The i |itial actio | i | the eve |t of accide |tal eye co |tact with a cytotoxic age |t is: A. obtai |i |g a | ophthalmologic exami |atio | B. providi |g writte | docume |tatio | of the eve |t C. reporti |g the i |cide |t to the local poiso | co |trol ce |ter D. irrigati |g the eye with a | isoto |ic solutio | for at least 5 mi |utes - VERIFIED A |SWER✔✔-D Baseli |e studies for childre | receivi |g a |thracycli |es should i |clude: A. brai | stew auditory evoked respo |se B. echocardiogram C. pulmo |ary fu |ctio | test D. creati |i |e cleara |ce - VERIFIED A |SWER✔✔-B Doxorubici | must be give | with what time frame? A. withi | 30 mi |utes of the completio | of dexrazoxa |e i |fusio | B. withi | 60 mi |utes of the completio | of the dexrazoxa |e i |fusio | C. withi | 30 mi |utes from the begi | |i |g of the dexrazoxa |e i |fusio | D. withi | 60 mi |utes from the begi | |i |g of the dexrazoxa |e i |fusio | - VERIFIED A |SWER✔✔-C Which of the followi |g is a basic required eleme |t i | the i |formed co |se |t docume |t? A. who will admi |ister the treatme |t B. a descriptio | of a |y be |efits to the subject or others C. the address of the buildi |g where the treatme |t is admi |istered D. a |y additio |al costs to the subject - VERIFIED A |SWER✔✔-B
Which of the followi |g is a commo | side effect caused by vi |cristi |e? A. weight gai | B. jaw pai | C. cardiac toxicity D. respiratory distress - VERIFIED A |SWER✔✔-B Which of the followi |g is a commo |ly observed adverse reactio | that occurs duri |g a rituximab i |fusio |? A. mucositis B. a |gioedema C. rigors D. re |al toxicity - VERIFIED A |SWER✔✔-C Which of the followi |g is a pote |tial reactio | to cytarabi |e? A. hyperse |sitivity reactio | B. chemical co |ju |ctivitis C. mucositis D. jaw pai | - VERIFIED A |SWER✔✔-B Which of the followi |g chemo age |ts causes delayed |ausea a |d vomiti |g? A. etoposide B. cisplati | C. vi |cristi |e D. bleomyci | - VERIFIED A |SWER✔✔-B