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Course Description for Biochemistry | CHEM 304, Exams of Biochemistry

Material Type: Exam; Class: Biochemistry; Subject: Chemistry; University: Thomas Jefferson University; Term: Unknown 2005;

Typology: Exams

Pre 2010

Uploaded on 08/17/2009

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COURSE: CHEMISTRY 304: Biochemistry
DESCRIPTION: Examines structure and function of biological macromolecules-
polysaccharides, proteins and nucleic acids; lipids; enzymes and metabolism; bioenergetics;
control mechanisms; hormones; body fluids; nutrition; and biochemical pathology. Lecture.
Prerequisite: Biology 110, 111 and Chemistry 101, 102
RECOMMENDED TEXTS: David L. Nelson and Michael M. Cox, Lehninger Principles of
Biochemistry, 4th edition, 2005. W.H. Freeman or Donald Voet and Judith G. Voet,
Biochemistry, 3rd Edition, 2004. John Wiley and Sons Publishers. ISBN: 0-471-19350-X
FORMAT: Closed book exam consisting of 95 objective questions with a multiple-choice,
matching and true/false format. In addition, there is a five-point essay question which will test
the student’s grasp of basic biochemical principles. Each objective question is worth one point.
The essay question is worth five points.
GRADING: Students must receive a “C” (73-76) in order to receive credit for a course taken as
a Challenge Exam.
TOPICS FOR STUDY
Amino acid structure
Protein structure and function
Levels of structure
Types of conjugated proteins
Hemoglobin structure and
function
Collagen structure and function
Denaturation
Enzymes
Substrate specificity
Coenzymes
Enzyme kinetics
Regulation of enzymatic activity
Carbohydrates
Sugar structure and function
Polysaccharide structure and
function
Lipids
Types of lipids
Physical properties of lipids
Biological membranes
Nucleic Acids
Structure of DNA and RNA
Metabolism
General principles of metabolism
Oxidation-reduction reactions
Glycolysis
Citric acid cycle
Electron transport system
Oxidative phosphorylation
Oxidation/Fatty acid
Ketone body formation
Amino acid deamination
DNA replication
DNA transcription
Translation and the genetic code
Metabolic diseases or conditions
Diabetes mellitis
Atherosclerosis
Ammonia intoxication
Sickle cell anemia
Lysosomal storage diseases

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COURSE: CHEMISTRY 304: Biochemistry

DESCRIPTION: Examines structure and function of biological macromolecules- polysaccharides, proteins and nucleic acids; lipids; enzymes and metabolism; bioenergetics; control mechanisms; hormones; body fluids; nutrition; and biochemical pathology. Lecture. Prerequisite: Biology 110, 111 and Chemistry 101, 102

RECOMMENDED TEXTS : David L. Nelson and Michael M. Cox, Lehninger Principles of Biochemistry , 4th^ edition, 2005. W.H. Freeman or Donald Voet and Judith G. Voet, Biochemistry, 3rd Edition, 2004. John Wiley and Sons Publishers. ISBN: 0-471-19350-X

FORMAT : Closed book exam consisting of 95 objective questions with a multiple-choice, matching and true/false format. In addition, there is a five-point essay question which will test the student’s grasp of basic biochemical principles. Each objective question is worth one point. The essay question is worth five points.

GRADING: Students must receive a “C” (73-76) in order to receive credit for a course taken as a Challenge Exam.

TOPICS FOR STUDY

Amino acid structure Protein structure and function

  • Levels of structure
  • Types of conjugated proteins
  • Hemoglobin structure and function
  • Collagen structure and function
  • Denaturation Enzymes
  • Substrate specificity
  • Coenzymes
  • Enzyme kinetics
  • Regulation of enzymatic activity Carbohydrates
  • Sugar structure and function
  • Polysaccharide structure and function Lipids
  • Types of lipids
  • Physical properties of lipids
  • Biological membranes

Nucleic Acids

  • Structure of DNA and RNA Metabolism
  • General principles of metabolism
  • Oxidation-reduction reactions
  • Glycolysis
  • Citric acid cycle
  • Electron transport system
  • Oxidative phosphorylation
  • Oxidation/Fatty acid
  • Ketone body formation
  • Amino acid deamination
  • DNA replication
  • DNA transcription
  • Translation and the genetic code Metabolic diseases or conditions
  • Diabetes mellitis
  • Atherosclerosis
  • Ammonia intoxication
  • Sickle cell anemia
  • Lysosomal storage diseases