Chronic Pancreatitis, Study Guides, Projects, Research of Medical Sciences

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Chronic Pancreatitis * Incidence: Rare condition , more common in males above 40 years. * Predisposing factors: 1) Chronic excess alcohol intake is the commonest cause . 2) chronic cholecysitis and stones in lower part of CBD is the second common cause . * Pathology: Slowly progressive destruction of the acinar cells , with increasing fibrosis and later calcification. Pancreas becomes indurated, nodular and adherent to surrounding structures. Pancreatic duct show multiple strictures with proximal dilatations. Gradual progressive loss of exocrine and endocrine functions of pancreas . Rare excessive fibrosis of head of pancreas > obstruction of lower part of CBD > Obstructive jaundice . Dilated Pancreatic Duct Fibrosis