Chemotherapy Certification Test: 2024 Exam Questions and Answers, Exams of Nursing

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CHEMO CERTIFICATION TEST LATEST 2024 EXAM 100

QUESTIONS AND CORRECT ANSWERS (VERIFIED ANSWERS)

|AGRADE

Mutations in genetic material from exposure to chemotherapy are termed? - ANSWER- Genotoxicity

The Vinca Alkaloids act in which phase where they prevent cell division? - ANSWER- M Phase Which of the following is likely the best way to ensure patient adherence to oral chemotherapy? - ANSWER- Schedule a phone call with the patient 3-5 days after therapy is initiated To address the dose-limiting toxicity of cyclophosphamide, what should discharge education for the patient include? - ANSWER- Encourage the intake of 2-3 liters of fluid per day Which of the following is true and should always be included in your discussion with patients when they go home after completing chemotherapy? - ANSWER- Sexual relations are often allowed as long as special precautions are taken Your patient asks if it is okay to have contact with family members during chemotherapy treatments. your best response is: - ANSWER- Normal contact and hugging and kissing are safe

PPE is required when administering chemotherapy using which of the following routes of administration? SATA - ANSWER- Select all answers. When caring for the patient who is receiving chemotherapy, you notice a puddle of urine beneath the foley bag on the floor. What should be your first action? - ANSWER- Remove unnecessary people from the area Which of the following may be included in a medical surveillance program? - ANSWER- Administer periodic questionnaires tracking contact with HD, use of PPE, and adverse events The NCCN guidelines recommend that with the agent you are administering that you should give the following three drug combination as antiemetic premedication:

1. 5-HT3 Antagonist
2. NK1 Antagonist
3. Corticosteroid - ANSWER- High emetic risk Prior to beginning any chemotherapy treatment, the nurse must perform an assessment where which of the following should occur? - ANSWER- Discussion with the patient about a history of drug, allergic, or transfusion reactions Certain chemotherapy agents are safely administered intrathecally but which of the following should NEVER be administered intrathecally as it is almost certain to be fatal? - ANSWER- Vincristine What is the very first thing you should do if you suspect a drug extravasation? - ANSWER- Stop the infusion Prevention of infection is so important for most oncology patients. Which of the following is no longer recommended to prevent infection?

• ANSWER- Neutropenic Diet

Which of the following is true about closed-system transfer devices? - ANSWER- Use of full PPE is still required If you are administering a chemotherapy agent that is an irritant know to have some vesicant properties, which of the following is true? - ANSWER- Treat an extravasation like it is a vesicant Out of the following, which is the safest way to administer vesicant therapy? - ANSWER- MOST LIKELY: IV push via the free flow method DEFINITELY NOT: Short infusion over 2 hours OR IV Continuous Infusion Which of the following is a concern when using oral chemotherapy agents? - ANSWER- Ensuring adherence to prescribed therapy With which of the following agents would the nurse need to educate the patient about ways to prevent acute, reversible neuropathy exacerbated by cold temperatures? - ANSWER- Oxiplatin You are educating your patient about febrile neutropenia. You discuss that febrile neutropenia is defined as an oral temperature greater than 100.4 lasting at least one hour with an ANC less than: - ANSWER- 500 You are discussing the advantages and disadvantages of oral chemotherapy with your patient. What is one of the advantages of oral chemotherapy that can ultimately lead to adherence issues with this type of therapy? - ANSWER- MOST LIKELY: Patient has an increased sense of control over treatment DEFINITELY NOT: Dosing schedules are straightforward... OR The convenience for the patient of taking medication at home

According to the ONS chemotherapy and biotherapy guidelines and recommendations for practice and the ONS/ASCO chemotherapy administration safety standards, how often should education and competency evaluation regarding chemotherapy administration be performed? - ANSWER- When hired and annually thereafter You are scheduling a meeting to remind the staff about the proper use of PPE to ensure decreased risk of HD exposure. who, besides the nurses, should attend? - ANSWER- All of the above. Which of the following safeguards should be taken to better prevent exposure to HD? - ANSWER- Flush the toilet with the lid down or place a plastic backed pad over the toilet When intrathecal chemotherapy is prepared for administration, what additional safety step beyond the usual chemotherapy safety checks, must be followed? - ANSWER- Specialized labeling and handling If a nurse is pregnant or breastfeeding, the ASCO/ONS recommendation is for the employer to? - ANSWER- Offer alternative duty to protect against HD exposure If you have an accidental exposure of HD on your clothes and skin, what should be your first or initial response? - ANSWER- Remove the affected clothing immediately When is it necessary to wear a NIOSH-approved respirator? - ANSWER- When cleaning up a hazardous drug spill Totect - ANSWER- Anecdote for Doxorubicin Warm Compress - ANSWER- Plant alkaloids and etoposide Bleomycin - ANSWER- bad for the lungs

Leucovorin - ANSWER- potentiates the effects of 5-FU and decreases the effect of MTX Calvert Formula Components - ANSWER- Area under the curve (AUC) Carboplatin Creatinine Clearance Aromatase Inhibitors - ANSWER- used for postmenopausal women- osteoporosis Vesicant Administration - ANSWER- Prior to non-vesicant drugs Through a central line or small gauge peripheral line

• blood return Cytarabine - ANSWER- Assess gross motor movement and coordination Capillary Leak Syndrome S/S - ANSWER- HYPOtension and decreased UOP Most feared symptom of cancer - ANSWER- nausea/vomiting For CD20+ NHL - ANSWER- Rituximab S/E Anti-angiogenesis agents - ANSWER- bleeding events delayed wound healing thrombotic events Asparaginase - ANSWER- Test dose is given prior Hypersensitivity Drugs - ANSWER- Rituxan Trastuzumab Paclitacel Cabazitaxel Cytostatic Agents - ANSWER- slow the growth of cancer cell

ANC - ANSWER- (poly+bands)WBC 1500 - ANSWER- Neutropenic Level Thalidomide - ANSWER- cannot be given to pregnant women Doxorubicin - ANSWER- urine=red IV Push Chemo - ANSWER- Always administer through free flowing IV Ifosfamide - ANSWER- watch urine for blood Steps to Take of a Chemo Spill - ANSWER- 1. ensure safety of pt and contain the spill

2. put on protective apparel from spill kit and place chemo bag in waste container
3. place contaminated linens in linen bag and mark per policy
4. wash your hands & document Flare Reaction - ANSWER- transient redness along the vein without pain Delayed Nausea - ANSWER- occurring after chemo Oxaliplatin - ANSWER- Cod sensitivity Myelosuppression - ANSWER- Most common dose limiting toxicity in cancer patients Paclitaxel - ANSWER- assess neurotoxicity- have pt pick up coin Tumor Lysis Syndome - ANSWER- 1. hyperkalemia
5. hyperphosphatemia

3. hyperuricemia
4. hypocalcemia IL2 - ANSWER- risk of hypotension Atropine - ANSWER- used to treat early diarrhea from Irinotecan (Camptosar) Capecitibe - ANSWER- risk of hand and foot syndrome Extravasation - ANSWER- possible with positive blood return Premeds foor Pemetrexed - ANSWER- B12 and folic acid Rapid infusion of Etoposide (S/E) - ANSWER- hypotension Hormonal Therapy - ANSWER- class of drug prescribed for a pt that is estrogen or progesterone receptor positive Methotrexate - ANSWER- given intrathecally Fludarabine - ANSWER- physicians will often treat prophylactically with antibiotics when this is prescribed Radiosensitizer - ANSWER- Gemcitabine 3 Hormonal Therapies - ANSWER- -anastrozole (Armidex) -biculatamide (Casodex) -Tamoxifen (Soltaox) 3 Drugs can cause cardiac toxicity - ANSWER- doxorubicin traztuzmab (herceptin) pertuzamab (perjeta)