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Chargaff's Rule​, Slides of Genetics

A. Read the text about Erwin Chargaff on the back page. EQ: How are Chargaff's results evidence for the base pairings in DNA? B. Graph the following data.

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2021/2022

Uploaded on 09/27/2022

gaurish
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Chargaff’s Rulename_________________________ per____
Due Wednesday 9/11 - graded
A. Read the text about Erwin Chargaff on the back page
EQ: How are Chargaff’s results evidence for the base pairings in DNA?
B. Graph the following data. Use color in your graph.
Think about how you will show the data. What is on the x-axis and what is on the y-axis?
Species
DNA Bases
% Adenine
% Cytosine
% Guanine
% Thymine
Yeast
31.3
17.1
18.7
32.9
Crab
47.3
2.7
2.7
47.3
Rat
28.6
21.5
21.4
28.5
Human
30.9
19.9
19.3
29.9
TITLE KEY
pf3
pf4

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Download Chargaff's Rule​ and more Slides Genetics in PDF only on Docsity!

Due Wednesday 9/11 - graded

A. Read the text about Erwin Chargaff on the back page

EQ: How are Chargaff’s results evidence for the base pairings in DNA?

B. Graph the following data. Use color in your graph.

Think about how you will show the data. What is on the x-axis and what is on the y-axis? Species DNA Bases % Adenine % Cytosine % Guanine % Thymine Yeast 31.3 17.1 18.7 32. Crab 47.3 2.7 2.7 47. Rat 28.6 21.5 21.4 28. Human 30.9 19.9 19.3 29. TITLE KEY

ANALYSIS QUESTIONS

  1. Which base (A, C, G, or T) appears in a similar/close to amount as a. thymine in yeast? _________________________________ b. cytosine in rats? _____________________________________ c. guanine in crabs? __________________________________ d. adenine in humans? _______________________________
  2. Chargaff’s experiment and data help us to understand that each base in DNA only bonds with one other base. Explain how his data is evidence for base pairings. Use actual data in your answer.
  3. You have just discovered Chargaff’s Rule! Why do you think different organisms have different amounts of A, C, G, & T? (HINT: What is different between organisms?)

Erwin Chargaff (1905-2002) was one of many scientists studying DNA in the 1940’s. He was interested

in the amount (%) of each base chemical compared to each other and how they were different across different organisms. Some of his results are in the table on the first page. He contributed the base pair rule to the discovery of the structure of DNA. He published his findings in 1950. Genetics: understand why structural changes to genes (mutations) may be harmful, beneficial or neutral to the structure and function of an organism. Highly Proficient (4) Proficient (3) Close to Proficient (2) Developing (1) ❏ Graph is high quality using and represents the data at a high level. ❏ Chimpanzee question in answered with thought and evidence. ❏ Data is used as evidence ❏ Graph shows the data ❏ Analysis questions are complete and show thought. ❏ Graph is incomplete or incorrect. ❏ Graph does not show the data clearly enough. ❏ Data is not used as evidence. ❏ Work is incomplete or needs more detail. ❏ no understanding is shown ❏ Mostly incomplete and/or incorrect.