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Definitions for key terms related to gene expression and protein synthesis, including alkaptonuria, transcription, mrna, translation, ribosomes, and various stages and components of the process. It also covers the differences between bacterial and eukaryotic systems.
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Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. The process by which DNA directs the synthesis of proteins. TERM 2
DEFINITION 2 Alkaptonuria (black urine disease or alcaptonuria) is a rare inherited genetic disorder of phenylalanine and tyrosine metabolism. Urine darkens upon exposure to the air TERM 3
DEFINITION 3 synthesis of RNA under the direction of DNA TERM 4
DEFINITION 4 Messenger RNA (mRNA) is a molecule of RNA encoding a chemical "blueprint" for a protein product. It carries a genetic message from the DNA to the protein synthesizing machinery of the cell TERM 5
DEFINITION 5 the synthesis of a polypeptide, occurs under the direction of mRNA
complex particles that facilitate the orderly linking of amino acids into polypeptide chains. TERM 7
DEFINITION 7 Transcription and translation occur in all organisms TERM 8
DEFINITION 8 Bacteria do not have nuclei, their DNA is not segregated from ribosomes and the other protein-synthesizing equipment. This lack of segregation allows translation of an mRNA to begin while its transcription is still in progress In a Eukaryotic cell the nuclear envelope seperates transcription from translation in space and time. Transcription occurs on the nucleus, and mRNA is transported in the cytoplasm, where translation occurs TERM 9
DEFINITION 9 the initial RNA transcript from any gene, including those coding for RNA that is not translated into protein TERM 10
DEFINITION 10 the genetic instructions for a polypeptide chain are written in in the DNA as a series of nonoverlapping, three nucleotide words
Pries the two strands of DNA apart and joins the RNA nucleotides as they base pair along the DNA template TERM 17
DEFINITION 17 No TERM 18
DEFINITION 18 the DNA sequence where RNA polymerase attaches and intiates transcription TERM 19
DEFINITION 19 signals the end of transcription TERM 20
DEFINITION 20 The stretch of DNA that is transcribed into an RNA molecules is called a transcription unit.
RNA polymerase II TERM 22
DEFINITION 22 Intiation, Elongation, and Termination. TERM 23
DEFINITION 23 Mediate the binding of RNA polymerase and the initiation of transcription. TERM 24
DEFINITION 24 the whole complex of transcription factors and RNA polymerase II bound to the promotor. TERM 25
DEFINITION 25 The TATA box is a DNA sequence found in the promoter region of genes in archaea and eukaryotes ; approximately 24% of human genes contain a TATA box within the core promoter.
splicing is a modification of an RNA after transcription, in which introns are removed and exons are joined. TERM 32
DEFINITION 32 An intron is a DNA region within a gene that is not translated into protein. TERM 33
DEFINITION 33 A DNA region within a gene that is expressed TERM 34
DEFINITION 34 several different snRNPS join with additional proteins to form an even larger assembly. This is almost as big as a ribosome. TERM 35
DEFINITION 35 RNA molecules that function as enzymes
some introns regulate gene activity. The splicing itself is necessary for the passage of the mRNA from the nucleus into the cytoplasm TERM 37
DEFINITION 37 Definition