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Call for Chapters Congenital Heart Disease, Summaries of Molecular biology

Call for Chapters: Etiology of Congenital Heart Disease: Insights from Teratology, Genetics,

Typology: Summaries

2024/2025

Uploaded on 05/05/2025

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Call for Chapters: The Multifactorial Etiology of Congenital Heart Disease:
Insights from Teratology, Genetics, and Exposomics
https://www.igi-global.com/publish/call-for-papers/call-details/8727
Proposals Submission Deadline: May 4, 2025
Full Chapters Due: June 27, 2025
Submission Date: June 27, 2025
Introduction
Congenital Heart Disease (CHD) remains one of the most prevalent and challenging congenital anomalies, affecting approximately 1% of all
live births worldwide. The etiology of CHD is complex, involving an intricate interplay of genetic, environmental, and exposomic factors. This
book aims to provide a comprehensive exploration of the teratogenic, genetic, and exposomic influences on the development of both syndromic
and non-syndromic CHD, addressing existing knowledge gaps and presenting cutting-edge research in this rapidly evolving field.
The book will explore the historical perspective on CHD etiology, tracing the evolution of our understanding from purely genetic models to the
current multifactorial paradigm. A significant portion of the book will be dedicated to exploring the non-genetic factors underlying CHD. The
exposomic perspective on CHD development will be a key focus of the book, reflecting the growing recognition of the importance of
environmental influences on fetal cardiovascular development. The book will also delve into the complex genetic landscape of non-syndromic
CHD, while discussing monogenic models, genetic heterogeneity, and the emerging understanding of polygenic and oligogenic contributions to
CHD risk. The book chapters will present recent advances in high-resolution metabolomics and the integration of omics technologies,
highlighting their potential to uncover complex gene-environment interactions in CHD etiology. Contents will address the challenges and
opportunities in translating research findings into clinical practice, including the potential for personalized prevention and treatment
strategies based on individual genetic and exposomic profiles.
Recommended Topics
• Etiological distinction in Syndromic vs. non-syndromic CHD • Teratogenic Factors in CHD Development • Rubella, Alcohol, PAH, plastics,
VOCs, infection, radiation • Environmental Metabolism Disrupting Chemicals • Metabolic Memory: Focus on Mitochondrial Function •
Medication-induced CHD: Lithium, retinoic acid, and anticonvulsants • Environmental teratogens: Industrial, occupational exposure,
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Download Call for Chapters Congenital Heart Disease and more Summaries Molecular biology in PDF only on Docsity!

Call for Chapters: The Multifactorial Etiology of Congenital Heart Disease:

Insights from Teratology, Genetics, and Exposomics

https://www.igi-global.com/publish/call-for-papers/call-details/

Proposals Submission Deadline: May 4, 2025 Full Chapters Due: June 27, 2025 Submission Date: June 27, 2025

Introduction

Congenital Heart Disease (CHD) remains one of the most prevalent and challenging congenital anomalies, affecting approximately 1% of all live births worldwide. The etiology of CHD is complex, involving an intricate interplay of genetic, environmental, and exposomic factors. This book aims to provide a comprehensive exploration of the teratogenic, genetic, and exposomic influences on the development of both syndromic and non-syndromic CHD, addressing existing knowledge gaps and presenting cutting-edge research in this rapidly evolving field. The book will explore the historical perspective on CHD etiology, tracing the evolution of our understanding from purely genetic models to the current multifactorial paradigm. A significant portion of the book will be dedicated to exploring the non-genetic factors underlying CHD. The exposomic perspective on CHD development will be a key focus of the book, reflecting the growing recognition of the importance of environmental influences on fetal cardiovascular development. The book will also delve into the complex genetic landscape of non-syndromic CHD, while discussing monogenic models, genetic heterogeneity, and the emerging understanding of polygenic and oligogenic contributions to CHD risk. The book chapters will present recent advances in high-resolution metabolomics and the integration of omics technologies, highlighting their potential to uncover complex gene-environment interactions in CHD etiology. Contents will address the challenges and opportunities in translating research findings into clinical practice, including the potential for personalized prevention and treatment strategies based on individual genetic and exposomic profiles.

Recommended Topics

  • Etiological distinction in Syndromic vs. non-syndromic CHD • Teratogenic Factors in CHD Development • Rubella, Alcohol, PAH, plastics, VOCs, infection, radiation • Environmental Metabolism Disrupting Chemicals • Metabolic Memory: Focus on Mitochondrial Function • Medication-induced CHD: Lithium, retinoic acid, and anticonvulsants • Environmental teratogens: Industrial, occupational exposure,

Pollutants and toxicants • Toxicology and Toxicogenomics: Paternal Occupational conditions and medications • Social determinants: Infectious diseases, Nutritional factors and maternal diet • Hazard ratios of lifestyle and Occupational pollutants and toxicants • Geo-Spatial Analysis, Congenital Tumors, and Early life fetal Exposures • Noonan syndrome, Alagille syndrome, and Holt-Oram syndrome • Genetic testing and counseling in syndromic CHD • Non-syndromic CHD, monogenic models, genetic heterogeneity • Chromosomal aneuploidies, CNVs, 22q11. and deletion syndromes • Polygenic and oligogenic contributions to CHD risk. • Reproductive toxicants, Endocrine Disruptors • Epigenetic mechanisms in CHD development • Monogenic models of non-syndromic CHD • Genetic heterogeneity in isolated CHD • Advanced Technologies in CHD Research • ncRNAs and miRNAs in germ cell differentiation • Postnatal exposure metabolomics adductomics • Bioinformatics Exposome-wide association studies (ExWAS) • Biomarkers: Advances in genetic testing • Risk Factors in Per- and polyfluoroalkyl substances • Maternal phenylketonuria (PKU), Age: Separating direct and indirect effects • Congenital anomaly, CHD-cancer associations • Monozygotic twinning, Chorionicity in twin pregnancies • Assisted reproductive technologies and CHD risk in multiple births • Artificial intelligence and Machine learning Applications • High-resolution metabolomics using Saliva, Urine for early detection • Integrating exposomics with genomics and epigenomics • Proteomics Metabolomics and Systems biology approaches • Public health Policies in CHD Risk Assessment and Prevention • Preconception and prenatal screening for CHD risk factors • Fetal echocardiography Translating Research into Clinical Practice

Submission Procedure

Researchers and practitioners are invited to submit on or before May 4, 2025 , a chapter proposal of 1,000 to 2,000 words clearly explaining the mission and concerns of his or her proposed chapter. Authors will be notified by May 18, 2025 about the status of their proposals and sent chapter guidelines.Full chapters of a minimum of 10,000 words (word count includes APA references and related tables, 300dpi Images) are expected to be submitted by June 27, 2025 , and all interested authors must consult the guidelines for manuscript submissions at https://www.igiglobal.com/publish/contributor-resources/before-you-write/ prior to submission. All submitted chapters will be reviewed on a double anonymized review basis. Contributors may also be requested to serve as reviewers for this project. Note: There are no submission or acceptance fees for manuscripts submitted to this book publication, The Multifactorial Etiology of Congenital Heart Disease: Insights from Teratology, Genetics, and Exposomics. All manuscripts are accepted based on a double-anonymized peer review editorial process. All proposals should be submitted through the eEditorial Discovery®^ online

submission manager. https://www.igi-global.com/publish/call-for-papers/call-details/