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A pretest for an exam in the microbiology course (biol1011) focusing on various concepts related to microorganisms, their properties, and interactions with the human body. Topics include sterilization agents, antibiotics, healthcare-associated infections, and the immune system.
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What chemical agent is used for sterilization? - ✔️Ethylene Oxide (EtO) What does NOT achieve sterilization? - ✔️Pasteurization An agent used to reduce the number of bacteria on a toilet would most accurately be called a(n) - ✔️Disinfectant. Which one of the following does NOT belong with the others? Bacitracin, Cephalosporin, Monobactam, Penicillin, Streptomycin. - ✔️Streptomycin. Always in combination with other antituberculosis agents. What antibiotic is recommended for use against gram-negative bacteria? - ✔️Cephalosporin The antimicrobial drugs with the broadest spectrum of activity are - ✔️Tetracyclines. Which of the following statements about healthcare-associated infections is FALSE? A) They occur in compromised patients. B) They may be caused by opportunists. C) They may be caused by drug-resistant bacteria. D) They may be caused by normal microbiota. E) The patient was infected before hospitalization. - ✔️E) The patient was infected before hospitalization. Which of the following is NOT a reservoir of infection? A) a sick person B) a healthy person C) a sick animal D) a hospital E) None of the answers is correct; all of these can be reservoirs of infection. - ✔️E) None of the answers is correct; all of these can be reservoirs of infection. All of the following contribute to a pathogen's invasiveness EXCEPT A) toxins. B) capsules. C) cell wall components. D) hyaluronidase. E) coagulases. - ✔️A) toxins.
Siderophores are bacterial proteins that compete with the host's A) antibodies. B) red blood cells. C) iron-transport proteins. D) white blood cells. E) receptors. - ✔️C) iron-transport proteins. Which of the following statements about staphylococcal enterotoxin is FALSE? A) It causes vomiting. B) It causes diarrhea. C) It is an exotoxin. D) It is produced by Staphylococcus aureus growing in the host's intestines. E) It is a superantigen. - ✔️D) It is produced by Staphylococcus aureus growing in the host's intestines. Which of the following is an example of direct damage due to bacterial infection? A) the uncontrolled muscle contractions in Clostridium tetani infection B) the invasion and lysis of intestinal cells by E. coli C) the hemolysis of red blood cells in a staphylococcal infection D) the fever, nausea, and low blood pressure in a Salmonella infection E) the excessive secretion of fluids in a Vibrio cholera infection - ✔️B) the invasion and lysis of intestinal cells by E. coli Which pathogen and virulence factor are mismatched? A) Streptococcus pneumoniae - capsule B) Streptococcus pyogenes - M protein C) Clostridium - hyaluronidase D) Shigella sonnei - coagulase E) Neisseria gonorrhoeae - IgA protease - ✔️D) Shigella sonnei - coagulase Innate immunity A) is slower than adaptive immunity in responding to pathogens. B) is nonspecific and present at birth. C) involves a memory component. D) involves T cells and B cells. E) provides increased susceptibility to disease. - ✔️B) is nonspecific and present at birth. All of the following increase blood vessel permeability EXCEPT A) kinins. B) prostaglandins. C) lysozymes. D) histamine. E) leukotrienes. - ✔️C) lysozymes Which of the following is found normally in serum?
A) always present but inapparent at the time of hospitalization B) always acquired during the course of hospitalization C) always caused by medical personnel D) only a result of surgery E) always caused by pathogenic bacteria - ✔️B) always acquired during the course of hospitalization The LD50 is a... A) measure of pathogenicity B) dose that will cause an infection in 50% of the test population C) dose that will kill some of the test population D) dose that will cause an infection in some of the test population E) dose that will kill 50% of the test population - ✔️B) dose that will cause an infection in 50% of the test population Endotoxins are: A) associated with gram-positive bacteria B) specific in their method of action C) part of the gram-negative cell wall D) excreted from the cell E) none of these - ✔️C) part of the gram-negative cell wall
C) iodine D) either a or b E) neither a or b - ✔️B) chlorine PMN is another name for ___________________ cell. A) monocyte B) neutrophil C) lymphocyte D) eosinophil E) basophil - ✔️B) neutrophil The control center for fever development is located in the: A) midbrain B) cerebral cortex C) hypothalamus D) neutrophil E) tonsil - ✔️C) hypothalamus