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Class: BIOL - Molecular Biology; Subject: Biology / Biological Sciences; University: University of Waterloo; Term: Forever 1989;
Typology: Quizzes
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Small RNA TERM 2
DEFINITION 2 Demethylated thymine TERM 3
DEFINITION 3 Topological state-Base pairing is interrupted, molecule exhibits super coiling TERM 4
DEFINITION 4 Circular DNA without any super helical turn TERM 5
DEFINITION 5 Reduce the stress induced by twisting of the double helix
Think of the shoelace TERM 7
DEFINITION 7 Every 10 bp TERM 8
DEFINITION 8 Protein pushes --> infront of protein two strands wrap around eachother more than once every 10 bp --> turns are smaller TERM 9
DEFINITION 9 When B-DNA is twisting incredibly tightly around its axis TERM 10
DEFINITION 10 Protein pushes --> two strands become wrapped around eachother less than once every 10 bp --> turns are longer
-total# of times one strand of closed ds DNA encircles the other strandL = T + WL is constant in unbroken duplex DNA, so any change in T must be met with an equal and opposite change in supercoiling TERM 17
DEFINITION 17 Break one or both strands of DNA --> wind them tighter/looser --> rejoin ends TERM 18
DEFINITION 18 -negatively TERM 19
DEFINITION 19 Use topoisomerases ex. ProkaryotesTOPO I - nicking-closing enzyme that makes a cut in one strand (relaxing -ve super coil). Does not use ATP and changes L in steps of one.TOPO II
DEFINITION 20 Topo I - similar to bacterialTopo II - relaxes only supercoiled DNA --> cannot induce super coils