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Ativan (Lorazepam) Medication Card
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MEDICATION GENERIC: lorazepam TRADE: Ativan PHARMACOLOGIC CLASS: Anxiolytic; sedative-hypnotic; benzodiazepine
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[Cite your source here.] Effects (anti anxiety, sedative, hypnotic, and skeletal muscle relaxant) are mediated by the inhibitory neurotransmitter GABA. Action sites are thalamic, hypothalamic, and limbic levels of CNS. Management of anxiety disorders and for short-term relief of symptoms of anxiety. Also used for preanesthetic medication to produce sedation and to reduce anxiety and recall of events related to day of surgery. Known sensitivity to benzodiazepines; acute narrow-angle glaucoma; primary depressive disorders or psychosis; COPD; coma, shock, sleep apnea; acute alcohol intoxication; dementia; intraarterial administration; respiratory depression; pregnancy, and lactation. Caution in patients with renal or hepatic impairment, renal failure, organic brain syndrome, myasthenia Travis, pulmonary disease, suicidal tendency, GI disorders, and children younger than 12. Adult: PO – 2 - 3 mg/day in divided doses IM – 0.05 mg/kg IV – 4mg injected slowly at 2mg/min Geriatric: PO – 1 - 2 mg/day Injection site irritation, drowsiness, sedation, dizziness, weakness, disorientation, depression, sleep disturbance, confusion, hallucinations, blurred vision, N/V, abdominal discomfort, anorexia Alcohol; CNS depressants; anticonvulsants; cimetidine increases plasma levels (increases toxicity); may increase phenytoin levels; smoking decreases sedative and anti anxiety effects Monitor VS, CNS status, and ability to void following administration. Supervise ambulatory of older adult patients for at least 8 hours to prevent falling or injury. Supervise patients who exhibit depression with anxiety closely (possibility of suicide). Monitor lab tests: CBC and LFT’s with long-term therapy. Onset: 1-5 min IV; 15-30 min IM. Peak: 60-90 min IM; 2 hours PO Duration: 12-24 hours Do not drive for at least 24-48 hours after administration. Do not consume alcohol for at least 24-48 hours after administration. Notify prescriber if daytime psychomotor function is impaired. Terminate regimen gradually over a period of several days. CONTRAINDICATIONS & PRECAUTIONS: MECHANISM OF ACTION: (^) THERAPEUTIC CLASS & USE: ROUTE & DOSAGE: ADVERSE EFFECTS: ONSET/PEAK/DURATION: INTERACTIONS: PATIENT EDUCATION: NURSING ASSESSMENT: