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The function of peroxide in the synthesis of oxidized iodine through the action of tpo enzyme. It also explores the regulation of duox1 and duox2 peroxidase enzymes by the thyroid stimulating hormone.
Typology: Exercises
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● What purpose does peroxide have in the synthesis of oxidized iodine? ○ Peroxide acts as a substrate to TPO, oxidizing from there ● Which peroxidase enzyme is the rate limiting step: DUOX1 or DUOX2? ○ Both ● What hormone stimulates DUOX1 and DUOX2 activity? ○ Via the thyroid stimulating hormone