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The pentose phosphate shunt pathway (ppsp), a metabolic process where glucose is converted into nadph. The significance of nadph production on ca2+/nadph duox is also explored. After nadph oxidation, peroxide is synthesized and used as a substrate for thyroid peroxidase.
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● In the pentose phosphate shunt pathway, glucose is converted into what? ○ NADPH ● What effect does the pentose phosphate shunt pathway have on Ca2+/NADPH DUOX? ○ PPSP produces NADPH from glucose ● After NADPH becomes oxidized, what is the byproduct? What is it used for? ○ Peroxide is synthesized via NADPH oxidation; peroxide is used as a substrate for thyroid peroxidase
