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This document includes the most recent and verified real questions with correct answers from the 2025 APEA Pharmacology Exam. It covers essential topics such as drug classifications, mechanisms of action, adverse effects, pharmacokinetics and pharmacodynamics, safe prescribing practices, and evidence-based pharmacologic management for common conditions. Ideal for nurse practitioner students preparing for board exams and clinical pharmacology mastery. Keywords:
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Proscar what does it do Decreases the size of the prostate You should not take Viagra with Grapefruit juice What insulins are the have the shortest onset and duration? Asparat Lyspro glulisin (onset 5 - 15 min peak effect 1-2 hours can last 4- 6 hours) What insulin has the shortest onset and duration NPH What are the rapid acting insulins? Lispro (Humalog) Aspart (Novolog) Glulisine (Apidra) What is the drug of choice for type 2 DM Metformin
What does metformin do? reduces the production of glucose in the liver by suppressing glucogenesis --> it increases the muscles glucose uptake and use Why should patient take an aspirin daily? Antiplatelet prevention prevents stroke PE Heart attacks What is side effect of aspiring toxcitity Tinnitus What should you monitor while patient is taking Epoiten Blood pressure for HTN Black box warning for patients taking epogen what can it cause Tumor growth A pt with angina usually has Asthersclerosis What meds do you give if pt has asthersclerosis ASA nitro statin If you want to self donate blood what should you prescribe
What things should you consider when you prescribe metformin Hydration status AIC kidney function What should you asses prior to giving metformin Kidney function Gliptins work by Incretin system and indirectly increases insulin production GLP1 receptor agonist work by Directly binding to the pancreatic cells What labs do we check when we give iron after 4 weeks TIBC ferritin H&H How soon should we draw labs when we give iron 4 weeks NYHA Class I asymptomatic NYHA class 11
Angina with exertion NYHA classification 111 Angina with min activity NYHA class 4 Symptoms at rest What is the biggest TLC for angina Exercise, diet, lose weight What are two reason's why pt go into heart failure MI ischemia What can you not take with Flagyl (metronidazole) Alcohol When you take a medication that causes hepatotoxcity what is baseline lab Liver enzymes What do PA/NP able to prescribe Provide more access to care What trimester is most dangerous for pregnant pt to take a teratogenic medication First Women is breastfeeding when should they take medication
What are the side effects of stopping Backofen abruptly Hallucinations What do you give Backofen for Spacisity - MS, CP spinal cord injuries Rivastigmine (Exelon) given for Alzheimers When do you change Rivastigmine patch Every 24 hours daily Pt has frequent migraines what do you give Propranolol If pt has migraine but is asthmatic what medication do you give Topamax Patient oxycodone is stopped working what happened Pt built up tolerance have to go with something stronger Why do you not like prescribing methadone Strongest addictive need EKG yearly to monitor for prolonged QT intervals What is the biggest side effect of SSRI Tardive dyskensia What do you need to do before switching from SSRI to
MAo Wait two weeks If patient suffers from panic attacks what is med u give SSRI If pt is postmenopausal what med route do you give estrogen Transdermal - least side effects What is the biggest concern when given teenager an oral contraceptive, what would you give instead Compliance , would give depo shot (medroxyprogesterone acetate) When pt is taking oral contraceptives and they have a major surgery coming up what medication do you switch them to Progesterone only med to prevent blood clots What is androgen therapy given for Hypogonadism What is the concern when pt gains weight while on androgen therapy