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A comprehensive review of hypertension (htn), covering complications, markers, and treatment guidelines. It includes details on blood pressure assessment, lifestyle modifications, and medication management, such as ace inhibitors, beta blockers, and diuretics. The document also addresses htn crisis management and follow-up care, making it a valuable resource for medical students and healthcare professionals studying cardiovascular health. It offers insights into managing hypertension with co-existing diseases like diabetes and renal failure, providing a practical guide for clinical practice. This review is designed to help prepare for the ancc cardiac vascular certification exam.
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Complications of HTN "retinopathy, coronary artery disease, MI, CHF, PVD, nephropathy, TIA/CVA","Don't forget what it does to the vascular system." HTN markers widening pulse pressure, Na sensitive, LV hypertropy, increase CVP, renal-30-200 microalbumin, GFR <60-90, CV-decrease cognition, dementia, vision loss Pulse Pressure (PP) systolic BP - diastolic BP force generated w each beat; 120/80= PP 40; normal 40-60; >60 = arterial stiffness end organ damage
Vascular damage in heart- HF/ ACS/aortic dissection/aneuysm, kidney, retina, or brain-enccphalopathy, pulmonary edema, pre eclampsia Systemic Atrial Blood Pressure CO, PVR, Baroreceptors, fluid volume, HTN->GFR > diuresis > RAAS, Low BP - stimulates RAAS HTN
HTN crisis 180/110; > risk of stroke; decrease end organ damage HTN management Lifestyle modification: weight reduction, eating plan, reduce sodium, physical activity 30- 45min walks, moderation of alcohol Resistant HTN definition high despite 3 agents, triple therapy combo- Ace/Arb, CCB, Tzd, aldactone/ loop diuretic; NO ACE/ARBS in pregnancy Beta Blocker- end in 'OLOL' (slow HR & < BP)
bradycardia- hold if HR<60& SBP <100/ HF/ ED/ fatigue/ depression, avoid w COPD, Heart Block, masks hypoglycemia, >orthostatic BP
ACE- end in 'PRIL' lisinopril (blocks RAAS) s/e- angioedema-worse in blacks, dry cough, hyperkalemia, hypotension, RF, do not take K+suppl, wean off only, take 1hr before meals alpha blockers- end in "OSIN" doxazosin s/e orthostatic bp, tachy, ED, first dose syncope, avoid in elderly and liver issues TZD -good/cheap s/e- hypokalemia, ED, <Na, > risk gout, avoid w RF, > lithium absorption, > photosensitivity ARBS END IN 'SARTAN' losartan (block aldosterone and angiotension receptors)- if dry cough w ACE- use ARBs instead Loop Diuretics
HTN medicaton tx goals w co existing diseases HTN w DM- goal <140/90 first use ACE/ARB <RF; HTN w RF-goal <140/90 - <Na, first use ACE; post MI goal- first use BB; HF- first use ACE & alpha blockers