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When chemotherapy is used before primary treatment (surgery) to reduce the size of a solid tumor, it is called what? Correct Answer: Neoadjuvant Therapy Which of the following class of drugs is cell cycle non-specific and therefore can affect the cancer in any phase of the cell cycle? Correct Answer: Alkylating Agents Mutations in genetic material from exposure to chemotherapy are termed? Correct Answer: Genotoxicity The Vinca Alkaloids act in which phase where they prevent cell division? Correct Answer: M Phase Which of the following is likely the best way to ensure patient adherence to oral chemotherapy?
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When chemotherapy is used before primary treatment (surgery) to reduce the size of a solid tumor, it is called what? Correct Answer: Neoadjuvant Therapy Which of the following class of drugs is cell cycle non-specific and therefore can affect the cancer in any phase of the cell cycle? Correct Answer: Alkylating Agents Mutations in genetic material from exposure to chemotherapy are termed? Correct Answer: Genotoxicity The Vinca Alkaloids act in which phase where they prevent cell division? Correct Answer: M Phase Which of the following is likely the best way to ensure patient adherence to oral chemotherapy?
Correct Answer: Schedule a phone call with the patient 3-5 days after therapy is initiated To address the dose-limiting toxicity of cyclophosphamide, what should discharge education for the patient include? Correct Answer: Encourage the intake of 2-3 liters of fluid per day Which of the following is true and should always be included in your discussion with patients when they go home after completing chemotherapy? Correct Answer: Sexual relations are often allowed as long as special precautions are taken Your patient asks if it is okay to have contact with family members during chemotherapy treatments. your best response is: Correct Answer: Normal contact and hugging and kissing are safe Your patient had an extravasation, which is a vinca alkaloid class of chemotherapy. What do you teach them about caring for the site when they get home? Correct Answer: Apply a warm compress for 15 minutes, 4 times a day Which of the following actions reflect an understanding of safe-handling procedures? Correct Answer: Wear two pairs of chemotherapy-tested gloves and gown when handling HD exposed bodily fluids
When caring for the patient who is receiving chemotherapy, you notice a puddle of urine beneath the foley bag on the floor. What should be your first action? Correct Answer: Remove unnecessary people from the area Which of the following may be included in a medical surveillance program? Correct Answer: Administer periodic questionnaires tracking contact with HD, use of PPE, and adverse events The NCCN guidelines recommend that with the agent you are administering that you should give the following three drug combination as antiemetic premedication:
What is the very first thing you should do if you suspect a drug extravasation? Correct Answer: Stop the infusion Prevention of infection is so important for most oncology patients. Which of the following is no longer recommended to prevent infection? Correct Answer: Neutropenic Diet Which of the following is true about closed-system transfer devices? Correct Answer: Use of full PPE is still required If you are administering a chemotherapy agent that is an irritant know to have some vesicant properties, which of the following is true? Correct Answer: Treat an extravasation like it is a vesicant Out of the following, which is the safest way to administer vesicant therapy? Correct Answer: MOST LIKELY: IV push via the free flow method DEFINITELY NOT: Short infusion over 2 hours OR IV Continuous Infusion Which of the following is a concern when using oral chemotherapy agents? Correct Answer: Ensuring adherence to prescribed therapy
Correct Answer: Peripherally inserted central catheter with strong blood return You know from reviewing the ONS PEP resources on skin reactions, that the only intervention that is likely to be effective is/ Correct Answer: MOST LIKELY: Dose interruption or modification (on ONS website) DEFINITELY NOT: Antibiotics Your patient has just arrived and is neutropenic and has a fever of 101.5. What is the most important thing to do after you obtain the ordered cultures? Correct Answer: Administer empiric, broad spectrum antibiotics According to the ONS position "Education of the Nurse Administers and Cares for the Individual Receiving Chemotherapy and Biotherapy", which of the following is necessary of the nurse who administers chemotherapy? Correct Answer: They complete both a didactic component and a clinical practicum to chow competency with administration principles. Which of the following is the only time it is acceptable to take a verbal order? Correct Answer: Stop or hold chemotherapy Which statement describes how chemotherapy works? Correct Answer: Disrupts the cell cycle during reproduction
The benefits of combination therapy include: Correct Answer: Synergistic effect between drugs According to the ONS chemotherapy and biotherapy guidelines and recommendations for practice and the ONS/ASCO chemotherapy administration safety standards, how often should education and competency evaluation regarding chemotherapy administration be performed? Correct Answer: When hired and annually thereafter You are scheduling a meeting to remind the staff about the proper use of PPE to ensure decreased risk of HD exposure. who, besides the nurses, should attend? Correct Answer: All of the above. Which of the following safeguards should be taken to better prevent exposure to HD? Correct Answer: Flush the toilet with the lid down or place a plastic backed pad over the toilet When intrathecal chemotherapy is prepared for administration, what additional safety step beyond the usual chemotherapy safety checks, must be followed? Correct Answer: Specialized labeling and handling If a nurse is pregnant or breastfeeding, the ASCO/ONS recommendation is for the employer to?