Name_________________________
1
BIO 366 EXAM I โ September 18, 2014
MULTIPLE CHOICE QUESTIONS (4 points each, only one correct choice)
1. Which of the following RNA molecules is expected to display base-paired stem
regions that involve 11 hydrogen bonds?
a. 5โ-GCCGAAAACGGC-3โ
b. 5โ-GCUGAAAACGGC-3โ
c. 5โ-GGGGAAAACCCC-3โ
d. 5โ-CGGAAAACCGCG-3โ
e. 5โ-GUUGAAAACGGC-3โ
2. If a B-form duplex DNA molecule is 34 cm long, what is the approximate number of
base pairs in this molecule?
a. 105,000
b. 1,050,000
c. 10,500,000
d. 105,000,000
e. 1,050,000,000
3. Which of the following ribonucleotide features is responsible for cleavage of
phosphodiester bonds in RNA molecules under alkaline conditions?
a. presence of uridine base
b. single-stranded nature of RNA
c. hydroxyl groups on both the 2โ and 3โ positions on the ribose sugar
d. ability to form pseudoknots
e. phosphodiester bond is more exposed to solvent
4. Which of the following is a feature of RNA synthesis but not DNA synthesis?
a. release of pyrophosphate when a phosphodiester bond is formed
b. newly synthesized chains grow in the 5โ to 3โ direction
c. primer is not required to initiate chain synthesis
d. unwinding of the duplex DNA template is required
e. requires a multiple subunit enzyme
5. Which of the following correctly describes differences between prokaryotic and
eukaryotic mRNAs?
a. the 5โ end of eukaryotic mRNAs has a cap structure
b. some prokaryotic mRNAs are polycistronic
c. prokaryotic mRNAs have 3โ poly(A) tails
d. eukaryotic mRNA lack a 5โ untranslated sequence (5โ UTR)
e. a and b
